Creutzfeldt-Jakob disease: typical imaging findings

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Creutzfeldt-Jakob disease: typical imaging findings.

To cite: Felix-Morais R, Andrade LC, Rebelo O. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014203997 DESCRIPTION A 63-year-old woman, previously healthy, presented with a 2-month history of progressive memory impairment, disorientation and behavioural changes. Examination revealed dysphasia, cerebellar ataxia and hypertonia of her upper limbs. Stimulus-sensit...

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Creutzfeldt-Jakob disease: magnetic resonance imaging findings.

Rapidly progressive dementia in an adult with findings of bilateral, symmetric high signal intensity on T2-weighted sequences and normal findings on T1-weighted sequences predominantly in the deep grey matter is suggestive of Creutzfeldt-Jakob disease (CJD). The peripheral cortex may be involved, as it was in the present case. The absence of subcortical periventricular white matter high signal ...

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Creutzfeldt-Jakob disease: A case report

Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...

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Sporadic Creutzfeldt-Jakob disease (sCJD) is a rare transmissible disease caused by accumulation of pathological prion protein in the CNS. sCJD typically affects patients in their sixties. The median disease duration in sCJD (6 months) is shorter than in variant Creutzfeldt-Jakob disease (vCJD) (14 months). The clinical diagnosis in sCJD is supported by the detection of periodic sharp and slow ...

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ژورنال

عنوان ژورنال: Case Reports

سال: 2014

ISSN: 1757-790X

DOI: 10.1136/bcr-2014-203997